Reporting and handling missing values in clinical studies in intensive care units

A Vesin, E Azoulay, S Ruckly, L Vignoud… - Intensive care …, 2013 - Springer
Introduction Missing values occur in nearly all clinical studies, despite the best efforts of the
investigators, and cause frequently unrecognised biases. Our aims were (1) to assess the …

Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers

…, A Debernardi, B Jacquiau, AL Vitte, A Vesin… - Science translational …, 2013 - science.org
Activation of normally silent tissue-specific genes and the resulting cell “identity crisis” are
the unexplored consequences of malignant epigenetic reprogramming. We designed a …

[HTML][HTML] Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study

…, A Mikstacki, J Lipman, P Depuydt, A Vesin… - Intensive care …, 2012 - Springer
Purpose The recent increase in drug-resistant micro-organisms complicates the management
of hospital-acquired bloodstream infections (HA-BSIs). We investigated the epidemiology …

Impact of an intensive care unit diary on psychological distress in patients and relatives

…, F Pochard, F Lancrin, F Philippart, A Vesin… - Critical care …, 2012 - journals.lww.com
Objective: To assess the impact of an intensive care unit diary on the psychological well-being
of patients and relatives 3 and 12 months after intensive care unit discharge. Design: …

Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays

D Moreau, A Vesin, M Garrouste-Orgeas… - Chest, 2007 - Elsevier
Background Thrombocytopenia is common in ICU patients. The objective of this study was to
evaluate possible links between declining platelet counts early in the ICU stay and survival. …

Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults

…, E Canet, J Bohe, A Lepape, A Vesin… - American journal of …, 2012 - atsjournals.org
Rationale: Most vascular catheter-related infections (CRIs) occur extraluminally in patients
in the intensive care unit (ICU). Chlorhexidine-impregnated and strongly adherent dressings …

Opinions of families, staff, and patients about family participation in care in intensive care units

…, V Willems, JF Timsit, F Diaw, S Brochon, A Vesin… - Journal of critical …, 2010 - Elsevier
PURPOSE: The aims of the study were to assess opinions of caregivers, families, and patients
about involvement of families in the care of intensive care unit (ICU) patients; to evaluate …

Selected medical errors in the intensive care unit: results of the IATROREF study: parts I and II

M Garrouste-Orgeas, JF Timsit, A Vesin… - American journal of …, 2010 - atsjournals.org
Rationale: Although intensive care units (ICUs) were created for patients with life-threatening
illnesses, the ICU environment generates a high risk of iatrogenic events. Identifying …

Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis

M Bekaert, JF Timsit, S Vansteelandt… - American journal of …, 2011 - atsjournals.org
Rationale: Measuring the attributable mortality of ventilator-associated pneumonia (VAP) is
challenging and prone to different forms of bias. Studies addressing this issue have …

[HTML][HTML] The Iatroref study: medical errors are associated with symptoms of depression in ICU staff but not burnout or safety culture

M Garrouste-Orgeas, M Perrin, L Soufir, A Vesin… - Intensive care …, 2015 - Springer
Purpose Staff behaviours to optimise patient safety may be influenced by burnout, depression
and strength of the safety culture. We evaluated whether burnout, symptoms of depression …