[HTML][HTML] Drug-resistant tuberculosis 2020: where we stand
A Iacobino, L Fattorini, F Giannoni - Applied Sciences, 2020 - mdpi.com
Featured Application This comprehensive overview of drug-resistant tuberculosis will be useful
for researchers to expand their knowledge beyond mechanisms other than chromosomal …
for researchers to expand their knowledge beyond mechanisms other than chromosomal …
[HTML][HTML] Eradication of Drug-Tolerant Mycobacterium tuberculosis 2022: Where We Stand
A Lanni, A Iacobino, L Fattorini, F Giannoni - Microorganisms, 2023 - mdpi.com
The lungs of tuberculosis (TB) patients contain a spectrum of granulomatous lesions, ranging
from solid and well-vascularized cellular granulomas to avascular caseous granulomas. In …
from solid and well-vascularized cellular granulomas to avascular caseous granulomas. In …
[HTML][HTML] Fighting tuberculosis by drugs targeting nonreplicating Mycobacterium tuberculosis bacilli
A Iacobino, G Piccaro, F Giannoni… - The International …, 2017 - journals.lww.com
Current tuberculosis (TB) treatment requires 6 months of combination therapy with isoniazid
(INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol for active TB and 9 months of INH …
(INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol for active TB and 9 months of INH …
Stenotrophomonas maltophilia strains from cystic fibrosis patients: genomic variability and molecular characterization of some virulence determinants
M Nicoletti, A Iacobino, G Prosseda, E Fiscarelli… - International Journal of …, 2011 - Elsevier
The genetic relatedness of 52 Stenotrophomonas maltophilia strains, collected from various
environmental and clinical sources, including cystic fibrosis (CF) patients, as well as the …
environmental and clinical sources, including cystic fibrosis (CF) patients, as well as the …
Laboratory management for SARS-CoV-2 detection: a user-friendly combination of the heat treatment approach and rt-Real-time PCR testing
…, M Scaturro, G Errico, A Iacobino… - Emerging microbes & …, 2020 - Taylor & Francis
The RNA purification is the gold standard for the detection of SARS-CoV-2 in swab samples,
but it is dependent on the availability of chemical reagents. In this study, we evaluated the …
but it is dependent on the availability of chemical reagents. In this study, we evaluated the …
[HTML][HTML] Different configurations of SARS-CoV-2 spike protein delivered by integrase-defective lentiviral vectors induce persistent functional immune responses …
…, A Capocefalo, MV Chiantore, A Iacobino… - Frontiers in …, 2023 - frontiersin.org
Several COVID-19 vaccine strategies utilizing new formulations for the induction of neutralizing
antibodies (nAbs) and T cell immunity are still under evaluation in preclinical and clinical …
antibodies (nAbs) and T cell immunity are still under evaluation in preclinical and clinical …
Galleria mellonella as an in vivo model for assessing the protective activity of probiotics against gastrointestinal bacterial pathogens
C Scalfaro, A Iacobino, C Nardis… - FEMS microbiology …, 2017 - academic.oup.com
The antagonistic activity against gastrointestinal bacterial pathogens is an important property
of probiotic bacteria and a desirable feature for pre-selection of novel strains with probiotic …
of probiotic bacteria and a desirable feature for pre-selection of novel strains with probiotic …
Mycobacterium tuberculosis is selectively killed by rifampin and rifapentine in hypoxia at neutral pH
A Iacobino, G Piccaro, F Giannoni… - Antimicrobial agents …, 2017 - Am Soc Microbiol
The activities of rifampin, rifapentine, bedaquiline, PA-824, clofazimine, nitazoxanide, isoniazid,
amikacin, moxifloxacin, niclosamide, thioridazine, and pyrazinamide were tested against …
amikacin, moxifloxacin, niclosamide, thioridazine, and pyrazinamide were tested against …
[HTML][HTML] Activity of Drug Combinations against Mycobacterium abscessus Grown in Aerobic and Hypoxic Conditions
A Lanni, E Borroni, A Iacobino, C Russo, L Gentile… - Microorganisms, 2022 - mdpi.com
Infections caused by Mycobacterium abscessus (Mab), an environmental non-tuberculous
mycobacterium, are difficult to eradicate from patients with pulmonary diseases such as cystic …
mycobacterium, are difficult to eradicate from patients with pulmonary diseases such as cystic …
[HTML][HTML] Moxifloxacin Activates the SOS Response in Mycobacterium tuberculosis in a Dose- and Time-Dependent Manner
A Iacobino, G Piccaro, M Pardini, L Fattorini… - Microorganisms, 2021 - mdpi.com
Previous studies on Escherichia coli demonstrated that sub-minimum inhibitory concentration
(MIC) of fluoroquinolones induced the SOS response, increasing drug tolerance. We …
(MIC) of fluoroquinolones induced the SOS response, increasing drug tolerance. We …