Initially inappropriate antibiotic therapy |
Severely immunocompromised patients (such as neutropenia or stem cell transplant) |
Highly antibiotic-resistant pathogens: |
Pseudomonas aeruginosa |
Carbapenem-resistant Acinetobacter spp. |
Carbapenem-resistant Enterobacteriaceae |
Second-line antibiotic therapy (e.g. colistin, tigecycline) |