Patients in whom short duration of therapy may not be possible and in whom duration of therapy should be individualised
| Initially inappropriate antibiotic therapy |
| Severely immunocompromised patients (such as neutropenia or stem cell transplant) |
| Highly antibiotic-resistant pathogens: |
| Pseudomonas aeruginosa |
| Carbapenem-resistant Acinetobacter spp. |
| Carbapenem-resistant Enterobacteriaceae |
| Second-line antibiotic therapy (e.g. colistin, tigecycline) |