Association between chronic bronchitis (CB+) and the frequent exacerbator phenotype
| Model 1 | Model 2 | |||
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Subjects n | 924 | 878 | ||
| COPD CB+ | 4.13 (2.82–6.04) | <0.001 | 3.96 (2.67–5.88) | <0.001 |
| Male COPD CB+ | 3.21 (1.90–5.42) | <0.001 | 3.11 (1.82–5.31) | <0.001 |
| Female COPD CB+ | 5.16 (2.94–9.05) | <0.001 | 5.10 (2.83–9.20) | <0.001 |
Model 1: age and sex# adjusted; model 2: adjusted for age, sex# and pack-years of cigarette smoking. COPD: chronic obstructive pulmonary disease. #: unstratified analyses only.