Gene | Analysed samples n | Status | Patients n (%) |
TP53 | 250 | Wild-type | 129 (51.6) |
Mutant (exons 4-9) | 121 (48.4) | ||
KRAS | 249 | Wild-type | 203 (81.5) |
Mutant (codon 12) | 46 (18.5) | ||
TP53 wild-type | 35 (76.1) | ||
TP53 mutant | 11 (23.9) | ||
EGFR# | 130 | Wild-type | 113 (86.9) |
Mutant | 17 (13.1) | ||
TP53 wild-type | 11 (64.7)¶ | ||
TP53 mutant | 6 (35.3)¶ | ||
KRAS wild-type | 16 (95)¶ | ||
KRAS mutant | 1 (5)¶ |
#: the group of cases analysed includes only adenocarcinoma; ¶: where 17 is 100%.