Abstract
In asthmatics, we estimated the minimal clinically important difference for 3He MRI ventilation defect volume (110 mL) and ventilation defect percent (2%) which are similar to FEV1, suggesting that these biomarkers are suitable for use in clinical trials.
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Conflict of interest: Ms. Eddy has nothing to disclose.
Conflict of interest: Dr. Svenningsen has nothing to disclose.
Conflict of interest: Dr. McCormack has nothing to disclose.
Conflict of interest: Dr. Parraga has nothing to disclose.
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