fC beats·min−1 | | | |
BMPR2+ | 74±9 | 136±15+ | 94±9§ |
BMPR2- | 67±15 | 135±20+ | 85±21§ |
Controls | 74±11 | 132±17+ | 84±13§ |
mPAP# mmHg | | | |
BMPR2+ | 14±2 | 25±3+ | 28±5§ |
BMPR2- | 15±2 | 22±7+ | 27±5§ |
Controls | 15±3 | 21±7+ | 25±4§ |
Q L·min−1 | | | |
BMPR2+ | 6.2±1.0 | 11.3±1.5+ | 7.4±1.6 |
BMPR2- | 5.5±1.7 | 11.3±4.6 | 6.4±1.7§ |
Controls | 5.6±1.2 | 11.1±2.7+ | 6.8±2.2§ |
TPVR Wood units | | | |
BMPR2+ | 2.5±0.4 | 2.2± 0.3 | 3.8±1.2§ |
BMPR2- | 2.8±0.9 | 2.1±0.9+ | 3.9±1.9§ |
Controls | 2.8±0.8 | 2.1±0.9+ | 3.6±1.9§ |
TPVR/Sp,O2 Wood units·%−1 | | | |
BMPR2+ | 0.013±0.002 | | 0.033±0.004*,¶,§ |
BMPR2- | 0.014±0.002 | | 0.028±0.004§ |
Controls | 0.014±0.003 | | 0.028±0.004§ |
α %·mmHg−1 | | | |
BMPR2+ | 1.8±0.5*,¶ | 1.0±0.3*,¶,+ | 1.0±0.3§ |
BMPR2- | 3.4±0.4 | 1.5±0.4+ | 1.0±0.2§ |
Controls | 2.9±0.4 | 1.4±0.2+ | 1.0±0.1§ |
Mean α %·mmHg−1 | | |
BMPR2+ | 1.2±0.4* | |
BMPR2- | 2.1±0.2 | |
Controls | 1.5±0.9 | |
mPAP–Q slope mmHg·L−1·min | | |
BMPR2+ | 1.50±0.4 | |
BMPR2- | 1.75±0.6 | |
Controls | 1.71±0.6 | |